Impact of influenza vaccination on the risk of SARS-CoV-2 infection in a middle-aged group of people
| Autor: | Alicja Grzanka, Beata Galuszka, Andrzej Bozek, Renata Kozłowska |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
2019-20 coronavirus outbreak Pediatrics medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 030231 tropical medicine Immunology Population comparative effectiveness 03 medical and health sciences 0302 clinical medicine Influenza Human medicine Immunology and Allergy Humans 030212 general & internal medicine education Retrospective Studies Pharmacology education.field_of_study business.industry SARS-CoV-2 Vaccination virus diseases COVID-19 Retrospective cohort study Middle Aged humanities body regions Observational study immunotherapy business influenza Vaccine Research Article Research Paper |
| Zdroj: | Human Vaccines & Immunotherapeutics article-version (VoR) Version of Record |
| ISSN: | 2164-554X |
| Popis: | Aims: An observational study of a retrospective cohort was performed to assess the impact of influenza vaccination (IV) on the risk of SARS-CoV-2 infection in a population of middle-aged people for 8 weeks after IV and compared with an unvaccinated group. Patients and methods: Data from 1098 middle-aged patients (53.7 ± 4.7 years) after IV and 1205 unvaccinated patients (50.1 ± 6.8 years) were analyzed based on medical documentation. The inclusion criteria were age between 40 − 60 years and IV in the period from 1−30 September 2020. The incidence of infection with SARS-CoV-2 was confirmed by PCR and the classification of ICD-10 (U07.1). Results and conclusions: After IV, patients had significantly fewer SARS-CoV–2 infections than the unvaccinated patients (P = .017). The hazard ratio was 0.74 (95% CI: 0.54−0.89). IV may partially reduce the risk of SARS-CoV-2 infection. |
| Databáze: | OpenAIRE |
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