Study on repairing canine mandibular defect with porous Mg–Sr alloy combined with Mg–Sr alloy membrane
| Autor: | Man Yang, Shanning Zhang, Sun Xirao, Chun-Yu Kang, Yuan Zhao, Wang Chengyue |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Mg-Sr alloy Alloy 02 engineering and technology engineering.material Computed tomographic Biomaterials 03 medical and health sciences Bone volume fraction 0302 clinical medicine mandibular defects Porosity Research Articles technology industry and agriculture Mandible 030206 dentistry equipment and supplies 021001 nanoscience & nanotechnology mineralized collagen membrane Membrane guided bone regeneration Mg–Sr alloy engineering Mg–Sr alloy membrane 0210 nano-technology Fenestration Biomedical engineering |
| Zdroj: | Regenerative Biomaterials |
| ISSN: | 2056-3426 2056-3418 |
| Popis: | To discuss the feasibility of the application of porous Mg–Sr alloy combined with Mg–Sr alloy membrane in the repair of mandibular defects in dogs. The second and third mandibular premolars on both sides were extracted from six dogs. The model of mandible buccal fenestration bone defects were prepared after the sockets healed. Twelve bone defects were randomly divided into groups A and B, then Mg–Sr alloy was implanted in bone defects of group A and covered by Mg–Sr alloy membrane while Mg–Sr alloy was implanted in bone defects of group B and covered by mineralized collagen membrane. Bone defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4, 8 and 12 weeks. After 12 weeks, the healing of bone defects were evaluated by gross observation, X-ray microscopes and histological observation of hard tissue. Bone defects in each group were repaired. At 8 and 12 weeks, the gray value of group A was higher than that of group B (P |
| Databáze: | OpenAIRE |
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