Lymph node staging after primary systemic therapy in women with breast cancer and lymph node involvement at diagnosis

Autor: Eva, Acea-Figueira, Alejandra, García-Novoa, Carlota, Díaz Carballada, Alberto, Bouzón Alejandro, Carmen, Conde, Paz, Santiago Freijanes, Joaquín, Mosquera Oses, Benigno, Acea-Nebril
Rok vydání: 2022
Předmět:
Zdroj: Cirugía Española (English Edition).
ISSN: 2173-5077
DOI: 10.1016/j.cireng.2022.06.007
Popis: The main objective of this study is to analyze the efficacy of combined axillary marking (lymph node clipping and sentinel lymph node biopsy (SLNB)) for axillary staging in patients with primary systemic treatment (PST) and pathologically confirmed node-positive breast cancer at diagnosis. The secondary objective is to determine the impact of lymph node marking in the suppression of axillary lymph node dissection (ALND) in the study group.We conducted a prospective study in which lymph node staging was performed using wire localization of positive lymph nodes and a SLNB with dual tracer. All patients who presented no metastatic involvement of the sentinel lymph node (SLN) or clip/wire-marked lymph node were spared an ALND. The multidisciplinary committee agreed on axillary treatment for patients with lymph node involvement.Eighty one patients met the inclusion criteria. We identified and extirpated the clip/ wire-marked node in 80 of 81 patients (98.8%), with SLNB performed successfully in 88,9% of patients. The SLN and wire-marked node matched in 78.9% of patients; 76.2% of patients did not undergo ALND.The combined axillary marking (clip and SLNB) in patients with metastatic lymph node at diagnosis and PST offers a high identification rate (98.8%) and a high correlation between the wire-marked lymph node and the SLN (78.9%). This procedure has enabled the suppression of ALND in 76.2% of patients.
Databáze: OpenAIRE
Externí odkaz: