The configuration of mitiromycin and its derivation from mitomycin B

Autor:	Noriaki Hirayama, Masaji Kasai, Kunikatsu Shirahata, Motomichi Kono
Rok vydání:	1991
Předmět:	Pharmacology Antibiotics Antineoplastic Magnetic Resonance Spectroscopy Molecular Structure Spectrophotometry Infrared Stereochemistry Chemistry Molecular Conformation Mitomycin B Mass Spectrometry Mitomycins Absolute structure Computational chemistry Mitiromycin Drug Discovery Molecule
Zdroj:	The Journal of Antibiotics. 44:309-312
ISSN:	1881-1469 0021-8820
DOI:	10.7164/antibiotics.44.309
Popis:	The configuration of mitiromycin (2) was first determined by NMR experiments including the NOE technique. The absolute structure of 2 was related to mitomycin B (3) because 2 was derived from 3 under basic conditions. The ketonic form 4 was presumed to be involved in the generation of 2.
Databáze:	OpenAIRE
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