Prognostic Value of Reading-to-Reading Blood Pressure Variability Over 24 Hours in 8938 Subjects From 11 Populations
| Autor: | Edoardo Casiglia, Masahiro Kikuya, Valérie Tikhonoff, Sofia Malyutina, José Boggia, Lutgarde Thijs, Katarzyna Stolarz-Skrzypek, Tatiana Kuznetsova, Yutaka Imai, H. Ibsen, Tine W. Hansen, Kalina Kawecka-Jaszcz, Kristina Björklund-Bodegård, Tom Richart, C Torp-Pedersen, Yan Li, Lars Lind, Jan A. Staessen, Ji-Guang Wang, Eoin O'Brien, Takayoshi Ohkubo, E Sandoya, Jørgen Jeppesen, Eamon Dolan, Yuri Nikitin |
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| Přispěvatelé: | Epidemiologie, RS: CARIM School for Cardiovascular Diseases |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Questionnaires medicine.medical_specialty Ambulatory blood pressure Databases Factual Diastole Blood Pressure 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine population science Risk Factors Surveys and Questionnaires Internal medicine Internal Medicine Humans Medicine risk factors 030212 general & internal medicine Risk factor ambulatory blood pressure Proportional Hazards Models business.industry Proportional hazards model Incidence Hazard ratio Blood Pressure Monitoring Ambulatory Middle Aged Prognosis Circadian Rhythm 3. Good health Surgery Blood pressure Cardiovascular Diseases Cohort Ambulatory Cardiology Female epidemiology blood pressure variability business |
| Zdroj: | Hypertension, 55(4), 1049-U419. LIPPINCOTT WILLIAMS & WILKINS |
| ISSN: | 1524-4563 0194-911X |
| Popis: | In previous studies, of which several were underpowered, the relation between cardiovascular outcome and blood pressure (BP) variability was inconsistent. We followed health outcomes in 8938 subjects (mean age: 53.0 years; 46.8% women) randomly recruited from 11 populations. At baseline, we assessed BP variability from the SD and average real variability in 24-hour ambulatory BP recordings. We computed standardized hazard ratios (HRs) while stratifying by cohort and adjusting for 24-hour BP and other risk factors. Over 11.3 years (median), 1242 deaths (487 cardiovascular) occurred, and 1049, 577, 421, and 457 participants experienced a fatal or nonfatal cardiovascular, cardiac, or coronary event or a stroke. Higher diastolic average real variability in 24-hour ambulatory BP recordings predicted ( P ≤0.03) total (HR: 1.14) and cardiovascular (HR: 1.21) mortality and all types of fatal combined with nonfatal end points (HR: ≥1.07) with the exception of cardiac and coronary events (HR: ≤1.02; P ≥0.58). Higher systolic average real variability in 24-hour ambulatory BP recordings predicted ( P P ≥0.54). SD predicted only total and cardiovascular mortality. While accounting for the 24-hour BP level, average real variability in 24-hour ambulatory BP recordings added |
| Databáze: | OpenAIRE |
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