Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents
| Autor: | D. Clive Williams, Suzanne M. Cloonan, Robert B. P. Elmes, Kim N. Orange, Thorfinnur Gunnlaugsson |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Cytoplasm
Luminescence Pyridines chemistry.chemical_element Nanotechnology Biochemistry Catalysis chemistry.chemical_compound Colloid and Surface Chemistry medicine Organometallic Compounds Humans Cell Nucleus Luminescent Agents Microscopy Confocal Cellular imaging General Chemistry DNA Combinatorial chemistry Ruthenium Chemistry medicine.anatomical_structure chemistry Colloidal gold Nanoparticles Gold Nucleus HeLa Cells |
| Popis: | The synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h. |
| Databáze: | OpenAIRE |
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