Organic-inorganic hybrid coatings containing phosphorus precursors prepared by sol–gel on Ti6Al4V alloy: electrochemical and in-vitro biocompatibility evaluation
| Autor: | Violeta Barranco, I.E. Soliman, Carole C. Perry, Federico R. García-Galván, A. A. El hadad, Mohamed A. Mezour, Antonia Jiménez-Morales, Juan Carlos Galván, Graham J. Hickman |
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| Přispěvatelé: | Ministerio de Economía y Competitividad (España) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
In-vitro biocompatibility Biocompatibility General Chemical Engineering Material sanitario 02 engineering and technology 010402 general chemistry Electrochemistry Dimethyltrimethylsilylphosphite 01 natural sciences Dip-coating Corrosion Metal Electrochemical corrosion resistance Sol-gel coatings Materials Chemistry Organic-inorganic hybrid Tecnología médica Sol-gel Nanotecnología Nanocomposite Organic Chemistry Titanium alloy 021001 nanoscience & nanotechnology 0104 chemical sciences Surfaces Coatings and Films Chemical engineering Materiales nanoestructurados visual_art Prótesis visual_art.visual_art_medium 0210 nano-technology |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 0300-9440 |
| Popis: | The durability and long-term success of metallic implants are enhanced through the molecular scale design of biocompatible and corrosion resistant surface coatings. To pursue this hypothesis, we have developed a new class of organic-inorganic (O-I) hybrid nanocomposite coatings based on tetramethylorthosilicate (TMOS) and γ-methacryloxypropyltrimethoxysilane (MAPTMS) as organofunctional alkoxysilanes precursors and dimethyltrimethylsilylphosphite (DMTMSP) as a phosphorus precursor. Addition of DMTMSP to TMOS-MAPTMS hybrids increased the extent of intermolecular condensation and cross-linking observed. Both normal human osteoblast in-vitro biocompatibility and corrosion resistance were enhanced in coatings containing DMTMSP. Though increasing phosphorous content correlated with biocompatibility, a compromise in the amount of phosphorus incorporated would be required if corrosion resistance was the most desirable parameter for optimization, at least for single coat systems. Evaluation of the electrochemical behaviour and the in-vitro biocompatibility show that films prepared using these materials by dip coating onto Ti6Al4V alloys offer a promising alternative to simpler coatings and wholly metallic prostheses. The authors would like to acknowledge financial support from the Ministry of Economy and Competitiveness of Spain (MAT2015-65445-C2-1-R Project). |
| Databáze: | OpenAIRE |
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