A model for temporal heterogeneities of tumor blood flow
| Autor: | Paolo A. Netti, Rakesh K. Jain, Francesco Mollica |
|---|---|
| Přispěvatelé: | Mollica, F., Netti, PAOLO ANTONIO, Jain, R. |
| Rok vydání: | 2003 |
| Předmět: |
Pathology
medicine.medical_specialty Normal tissue Hemodynamics Biochemistry Capillary Permeability In vivo Neoplasms medicine Animals Humans Tumor growth Chemistry Models Cardiovascular Cell Biology Blood flow Temporal heterogeneities Capillaries medicine.anatomical_structure Regional Blood Flow Permeability (electromagnetism) Circulatory system Mathematical modeling Tumor blood flow Tumor vascular permeability Cardiology and Cardiovascular Medicine Blood Flow Velocity Blood vessel |
| Zdroj: | Microvascular Research. 65:56-60 |
| ISSN: | 0026-2862 |
| Popis: | Tumor blood flow (TBF) plays a fundamental role in tumor growth and treatment, and is characterized by spatial and temporal heterogeneities. Here we show that the interstitial fluid pressure (IFP), which is higher in tumoral tissue than in normal tissue, coupled with the tumor microvascular pressure (MVP) and the higher permeability of tumoral vessels, can explain the sustained oscillatory behavior of TBF, observed in vivo. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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