Dietary D-psicose, a C-3 epimer of D-fructose, suppresses the activity of hepatic lipogenic enzymes in rats
| Autor: | Hiroo Suzuki, Ken Izumori, Yoshitake Baba, Kei Takeshita, Tatsuhiro Matsuo, Mineo Hashiguchi |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Psicose medicine.medical_specialty Medicine (miscellaneous) Adipose tissue Fructose Biology Glucosephosphate Dehydrogenase chemistry.chemical_compound Random Allocation Internal medicine Abdomen medicine Animals Rats Wistar Soleus muscle Lipoprotein lipase Nutrition and Dietetics Carbohydrate Rats Fatty acid synthase Endocrinology Glucose chemistry Adipose Tissue Liver Lipogenesis biology.protein Epimer Fatty Acid Synthases |
| Zdroj: | Asia Pacific journal of clinical nutrition. 10(3) |
| ISSN: | 0964-7058 |
| Popis: | D-Psicose (D-ribo-2-hexulose), a C-3 epimer of D-fructose, is present in small quantities in commercial carbohydrate complexes or agricultural products. Wistar male rats were fed experimental diets which consisted of 5% D-psicose, cellulose, D-fructose or D-glucose for 28 days. Abdominal adipose tissue weight was significantly lower (P < 0.05) in rats fed the D-psicose diet than in rats fed a D-fructose and D-glucose diets, even though the four dietary groups were offered the same amount throughout the experimental period. Fatty acid synthase and glucose 6-phosphate dehydrogenase activities in the liver were significantly lower (P < 0.05) in rats fed the D-psicose diet than in rats fed the D-fructose and D-glucose diets. However, lipoprotein lipase activities in the heart, soleus muscle and perirenal adipose tissue were the same. These results suggest that a supplement of D-psicose in the diet suppresses hepatic lipogenic enzyme activities. The lower abdominal fat accumulation in rats fed a D-psicose diet might result from lower lipogenesis in the liver. |
| Databáze: | OpenAIRE |
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