Translation, Validation, Diagnostic Accuracy, and Reliability of Screening Questionnaire for Parkinsonism in Three African Countries

Autor:	Hanan Elrassas, Osigwe P. Agabi, Laura Aguado, Esther Cubo, Eman Hamid, Callixte Kuate, Njideka U Okubadejo, Asmaa Helmi, Caroline M. Tanner, Sara Calvo, Tamer Roushdy, Jacques Doumbe, Ali S. Shalash, Mohamed Essam, Oluwadamilola O. Ojo
Rok vydání:	2020
Předmět:	Male 0301 basic medicine medicine.medical_specialty Psychometrics Nigeria 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Rating scale Surveys and Questionnaires Statistical significance Epidemiology medicine Humans Dementia Cameroon Stage (cooking) Aged business.industry Parkinsonism Reproducibility of Results Montreal Cognitive Assessment Parkinson Disease Cognition Middle Aged Translating medicine.disease 030104 developmental biology Egypt Female Neurology (clinical) business 030217 neurology & neurosurgery Clinical psychology
Zdroj:	Journal of Parkinson's Disease. 10:1113-1122
ISSN:	1877-718X 1877-7171
DOI:	10.3233/jpd-202040
Popis:	BACKGROUND Availability of validated Parkinson's disease (PD) questionnaires in languages spoken in Africa will enable the conduct of epidemiological studies. OBJECTIVE The aims of the current study were to develop cross-cultural translated and validated Arabic and French versions of a PD screening questionnaire, and determine its diagnostic accuracy for recognition of parkinsonism in early and moderate-advanced PD in three countries (Cameroon (French), Egypt (Arabic), and Nigeria (English)). METHODS This cross-sectional study screened 159 participants (81 PD and 78 controls) using the PD screening questionnaire. The questionnaire was translated into Arabic and French versions using standard protocols. Cognitive function was assessed using the Montreal Cognitive Assessment and the Identification and Intervention for Dementia in Elderly Africans cognitive screen. Co-morbidity burden was documented using the Charlson Comorbidity Index. PD severity and stage were evaluated using the MDS Unified Parkinson Disease Rating Scale and the Hoehn and Yahr scale respectively. RESULTS Both PD patients and controls were matched regarding age, gender, education, and co-morbidity burden. The PD screening questionnaire scores were significantly higher in PD (median 8.0, IQR 6.0-10.0) in contrast to controls (0.0, IQR 0.0-0.0) (p
Databáze:	OpenAIRE
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