Photocatalytic Dehydrogenative Cross-Coupling of Alkenes with Alcohols or Azoles without External Oxidant

Autor:	Atul K. Singh, Aiwen Lei, Chunlan Song, Bowen Dou, Yiying Li, Linbin Niu, Hong Yi
Rok vydání:	2016
Předmět:	chemistry.chemical_classification Alkene 010405 organic chemistry General Chemistry General Medicine Bond formation Photochemistry 010402 general chemistry Redox Acceptor 01 natural sciences Catalysis 0104 chemical sciences Cobalt catalyst chemistry Enol ether Photocatalysis Coupling (piping)
Zdroj:	Angewandte Chemie (International ed. in English). 56(4)
ISSN:	1521-3773
Popis:	Direct cross-coupling between alkenes/R-H or alkenes/RXH is a dream reaction, especially without external oxidants. Inputting energy by photocatalysis and employing a cobalt catalyst as a two-electron acceptor, a direct C-H/X-H cross-coupling with H2 evolution has been achieved for C-O and C-N bond formation. A new radical alkenylation using alkene as the redox compound is presented. A wide range of aliphatic alcohols-even long chain alcohols-are tolerated well in this system, providing a new route to multi-substituted enol ether derivatives using simple alkenes. Additionally, this protocol can also be used for N-vinylazole synthesis. Mechanistic insights reveal that the cobalt catalyst oxidizes the photocatalyst to revive the photocatalytic cycle.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3900732a8cd6104c5062cd0f2422f2b8 https://pubmed.ncbi.nlm.nih.gov/27990726 Zobrazit plný text záznamu Plný text