The Fate of Unruptured Intracranial Vertebrobasilar Dissecting Aneurysm with Brain Stem Compression According to Different Treatment Modalities
| Autor: | Dong Young Cho, Jai Ho Choi, Youmie Park, Yurim Shin, Bum-Soo Kim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Adolescent medicine.medical_treatment 030218 nuclear medicine & medical imaging 03 medical and health sciences Young Adult 0302 clinical medicine Aneurysm Blood vessel prosthesis medicine Humans Radiology Nuclear Medicine and imaging Embolization cardiovascular diseases Child Watchful Waiting Stroke Coil embolization Aged Retrospective Studies Interventional business.industry Endovascular Procedures Retrospective cohort study Intracranial Aneurysm Middle Aged medicine.disease Embolization Therapeutic Blood Vessel Prosthesis Aortic Dissection Treatment Outcome Treatment modality Female Stents Neurology (clinical) Brain stem compression business Nuclear medicine 030217 neurology & neurosurgery Brain Stem |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X |
| Popis: | BACKGROUND AND PURPOSE: Unruptured intracranial vertebrobasilar dissecting aneurysms with brain stem compression are difficult to treat. In the present study, the clinical and radiologic outcomes of unruptured intracranial vertebrobasilar dissecting aneurysms with brain stem compression based on different treatment modalities were evaluated. MATERIALS AND METHODS: This study included 28 patients with unruptured intracranial vertebrobasilar dissecting aneurysms with brain stem compression treated from January 2009 to December 2017. Treatment methods were observation (n = 6), stent-assisted coil embolization (n = 9), parent artery occlusion (n = 6), and flow diversion (n = 7). The data of baseline characteristics, change of aneurysm size, retreatment rate, stroke occurrence, and alteration of the mRS score were obtained from retrospective chart review. RESULTS: The initial size of dissecting aneurysms was largest in the flow diversion group (22.5 ± 7.7 mm), followed by parent artery occlusion (20.3 ± 8.4 mm), stent-assisted coil embolization (11.7 ± 2.2 mm), and observation (17.8 ± 5.5 mm; P = .01) groups. The reduction rate of aneurysm size was highest in the parent artery occlusion group (26.7 ± 32.1%), followed by flow diversion (14.1% ± 28.7%), stent-assisted coil embolization (−17.9 ± 30.3%), and observation (−31.5 ± 30.8%; P = .007) groups. Additional treatment was needed in the observation (4/6, 66.7%) and stent-assisted coil embolization (3/9, 33.3%; P = .017) groups. Improvement of the mRS score on follow-up was observed in the flow diversion (6/7, 85.7%) and parent artery occlusion (4/6, 66.7%) groups but not in the stent-assisted coil embolization and observation groups. A worsened mRS score was most common in the observation group (4/6, 66.7%), followed by stent-assisted coil embolization (3/9, 33.3%), parent artery occlusion (2/6, 33.3%), and flow diversion (0/7, 0%) groups. CONCLUSIONS: When treating intracranial vertebrobasilar dissecting aneurysms with brain stem compression, parent artery occlusion and flow diversion should be considered to reduce aneurysm size and improve the mRS score. |
| Databáze: | OpenAIRE |
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