Quantification of burn induced extravasation of Evans blue albumin based on digital image analysis
| Autor: | Guy Heyden, Anders Jönsson, Jean Cassuto, Ulf Mattsson |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Continuous measurement Burn injury medicine.medical_specialty Health Informatics Rats Sprague-Dawley chemistry.chemical_compound Spectrophotometry Image Processing Computer-Assisted Medicine Animals Edema Evans Blue Skin medicine.diagnostic_test business.industry Abdominal skin Albumin Extravasation Computer Science Applications Surgery Rats chemistry Microscopy Fluorescence Digital image analysis business Burns Biomedical engineering Extravasation of Diagnostic and Therapeutic Materials |
| Zdroj: | Computers in biology and medicine. 28(2) |
| ISSN: | 0010-4825 |
| Popis: | The present study evaluated a non-invasive method based on digital image colour analysis that allows near-continuous quantification of extravasated Evans blue albumin after burn injury. A full-thickness burn was induced in the abdominal skin of rats, followed by injection of Evans blue dye. Tissue content of Evans blue were quantified using spectrophotometry, and compared with digital colour analysis. The non-invasive technique demonstrated a good correlation when compared to invasive spectrophotometry, but is superior by allowing near continuous measurement in the same subject and may be of value for evaluation of effective burn oedema-reducing treatment. |
| Databáze: | OpenAIRE |
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