Needle aspiration cytology of acinar-cell carcinoma of the pancreas: report of a case with diagnostic pitfalls and unusual ultrastructural findings
| Autor: | Gia-Khanh Nguyen, Ricci R. Villanueva, Phong Nguyen-Ho |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Pathology medicine.medical_specialty Histology Pancreatic disease Pathology and Forensic Medicine Predictive Value of Tests Pancreatic cancer Cytology medicine Carcinoma Humans Aged business.industry Carcinoma Acinar Cell Endoplasmic reticulum Biopsy Needle General Medicine Anatomy medicine.disease Zymogen granule Pancreatic Neoplasms medicine.anatomical_structure Acinar cell carcinoma of the pancreas Pancreas business |
| Zdroj: | Diagnostic cytopathology. 10(4) |
| ISSN: | 8755-1039 |
| Popis: | A case of histologically and ultrastructurally confirmed acinarcell carcinoma of the pancreas examined by needle aspiration cytology is reported. The aspirate showed isolated and loosely clustered cells with variable granular cytoplasm, and central or eccentrically located oval hyperchromatic nuclei dysplaying prominent nucleoli, suggesting a pancreatic neuroendocrine tumor. Numerous intracytoplasmic zymogen granules and several microtubules within cisternae of rough endoplasmic reticulum (MCRER) were found by electron microscopic study of metastatic tumor tissue. Cytodiagnostic pitfalls of this rare pancreatic cancer are discussed as well as the diagnostic value of MCRERs. © 1994 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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