Renal filtration function in patients with gout
| Autor: | A. V. Govorin, M. Yu. Mishko, Tatyana Medvedeva, Natalia Kushnarenko |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
arterial hypertension
medicine.medical_specialty Ambulatory blood pressure Urology Renal function RM1-950 urologic and male genital diseases chemistry.chemical_compound gout Internal medicine medicine Diseases of the circulatory (Cardiovascular) system Pharmacology (medical) Circadian rhythm Hyperuricemia glomerular filtration rate business.industry medicine.disease female genital diseases and pregnancy complications Gout Endocrinology chemistry RC666-701 Renal physiology Uric acid Therapeutics. Pharmacology Cardiology and Cardiovascular Medicine business chronic kidney disease Kidney disease |
| Zdroj: | Racionalʹnaâ Farmakoterapiâ v Kardiologii, Vol 12, Iss 4, Pp 380-384 (2016) |
| ISSN: | 2225-3653 1819-6446 |
| DOI: | 10.20996/1819-6446-2016-12-4-380-384 |
| Popis: | Aim. To study circadian blood pressure (BP) profile in patients with gout depending on the presence of arterial hypertension (HT) and their relationship to the renal filtration function. Material and methods. Patients with gout (n=87) were included into the study. All the patients underwent ambulatory BP monitoring (ABPM) with the assessment of circadian BP profile, determination of uric acid serum levels, glomerular filtration rate (GFR) was evaluated by CKD-EPI method. Depending on GFR level, all the patients were divided into 2 groups - with renal dysfunction or without one. Results. ABPM revealed circadian BP dysregulation in 55% of gout patients both with HT and without HT. Chronic kidney disease (CKD) was revealed in 72.4% of male patients, with the prevalence in patients with HT (76.6 vs 61%; p |
| Databáze: | OpenAIRE |
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