Ewing’s sarcoma of the maxillary sinus
| Autor: | Moustafa Al Khalil, Firas Nasser, Emaad Bin Mujeeb, Ousama Al Homsi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Ifosfamide Radiotherapy Maxillary sinus business.industry medicine.medical_treatment Induction chemotherapy Ewing's sarcoma medicine.disease Surgery Radiation therapy medicine.anatomical_structure Chemotherapy Medicine General Materials Science Sarcoma Ewing’s sarcoma business Sinus (anatomy) Etoposide medicine.drug |
| Zdroj: | Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 16:177-180 |
| ISSN: | 2090-0740 |
| DOI: | 10.1016/j.ejenta.2015.04.004 |
| Popis: | Ewing’s sarcoma is typically an aggressive, poorly differentiated tumor affecting children and young adults, it accounts for 4–6% of all primary bone tumors and facial primary localizations occur in only 1–4% of all cases, mostly in the mandible and calvaria. Paranasal sinus involvement is rare. A 22-year-old female was reviewed in Oral & Cranio Maxillofacial Surgery Department. She complained of swelling of the right paranasal area, of one-month duration, progressively increasing in size and associated with pain. The medical history was unremarkable, Contrast Enhanced Computed Tomography scan showed a destructive lesion of the anterior wall of the right maxillary sinus reaching up to the medial wall of the maxillary sinus, other paranasal sinus appearance was normal. Incisional biopsy proved it to be Ewing’s Sarcoma. She was treated by chemotherapy using Vincristine, Adriamycin, and Cyclophosphamide alternating with Etoposide & Ifosfamide and Radiotherapy, and this resulted in complete regression of the tumor. Repeated PET scans every 6 months did not suggest any recurrence of the right maxillary sinus tumor. We concluded that treatment by induction chemotherapy followed by radiation therapy leads to a favorable outcome in the above described case, avoiding the morbidity that can result from surgical options. |
| Databáze: | OpenAIRE |
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