Immune human lymphocytes produce an acid-labile alpha-interferon
| Autor: | D. B. Griffin, H. A. Band, P. C. L. Beverley, Frances R. Balkwill |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Immunology
Cross Reactions medicine.disease_cause Lymphocyte Activation Peripheral blood mononuclear cell Microbiology Immune system Antigen Interferon Influenza Human medicine Influenza A virus Concanavalin A Immunology and Allergy Animals Humans Lymphocytes Autoimmune disease biology Articles Haplorhini Hydrogen-Ion Concentration medicine.disease Influenza Vaccines Interferon Type I biology.protein Cattle Interferon type I medicine.drug |
| Zdroj: | The Journal of Experimental Medicine |
| Popis: | We have described in this paper a novel human interferon (IFN) with antigenic and cross-species reactivity of α-IFN and physicochemical properties of γ-IFN. This IFN is produced by normal peripheral blood mononuclear cells during an immune response but has also been associated with autoimmune disease (10). The system described here will be useful in elucidating the biological significance and cell of origin of this IFN. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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