HPMA and HEMA copolymer bead interactions with eukaryotic cells
| Autor: | Michael R. Borenstein, Cristina Duarte Vianna-Soares, Kadriye Ciftci, Kim Cherng-Ju |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Acrylate polymer
Acrylate Materials science Mechanical Engineering hydrophilic/hydrophobic beads cell attachment Bead Condensed Matter Physics Methacrylate Polyvinyl alcohol chemistry.chemical_compound adhesion chemistry Polymerization Mechanics of Materials visual_art Polymer chemistry visual_art.visual_art_medium Copolymer lcsh:TA401-492 General Materials Science lcsh:Materials of engineering and construction. Mechanics of materials Methyl methacrylate acrylate polymer Nuclear chemistry |
| Zdroj: | Materials Research, Vol 7, Iss 3, Pp 473-477 (2004) Materials Research, Volume: 7, Issue: 3, Pages: 473-477, Published: SEP 2004 Materials Research v.7 n.3 2004 Materials research (São Carlos. Online) Universidade Federal de São Carlos (UFSCAR) instacron:ABM ABC ABPOL |
| ISSN: | 1516-1439 |
| Popis: | Two different hydrophilic acrylate beads were prepared via aqueous suspension polymerization. Beads produced of a hydroxypropyl methacrylate (HPMA) and ethyleneglycol methacrylate (EDMA) copolymer were obtained using a polyvinyl alcohol suspending medium. Copolymers of 2hydroxyethyl methacrylate (HEMA), methyl methacrylate (MMA) and ethyleneglycol methacrylate (EDMA) beads were obtained using magnesium hydroxide as the suspending agent. Following characterization by scanning electron microscopy (SEM), nitrogen sorption analysis (NSA) and mercury intrusion porosimetry (MIP), the beads were cultured with monkey fibroblasts (COS7) to evaluate their ability to support cell growth, attachment and adhesion. Cell growth behavior onto small HPMA/EDMA copolymer beads and large HEMA/MMA/EDMA copolymer beads is evaluated regarding their hidrophilicity/hidrophobicity and surface roughness. |
| Databáze: | OpenAIRE |
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