Autoimmune Haemolytic Anaemia-A Spectrum of Presentation in Children
| Autor: | Ankita Patel, Sataroopa Mishra, Anirban Mandal, Amitabh Singh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Mycoplasma pneumoniae
Oseltamivir Response to therapy Clinical Biochemistry lcsh:Medicine Autoimmune hepatitis medicine.disease_cause Primary disease autoimmune hemolysis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine systemic lupus erythematosus immune system diseases 0502 economics and business Autoimmune haemolytic anaemias medicine 030212 general & internal medicine autoimmune hepatitis biology business.industry lcsh:R 05 social sciences Paediatrics Section General Medicine medicine.disease mycoplasma pneumoniae Corticosteroid therapy chemistry Immunology biology.protein 050211 marketing Antibody business |
| Zdroj: | Journal of Clinical and Diagnostic Research, Vol 11, Iss 9, Pp SR01-SR02 (2017) |
| ISSN: | 2249-782X |
| DOI: | 10.7860/jcdr/2017/27895.10646 |
| Popis: | Autoimmune Haemolytic Anaemias (AIHAs) are rare in children. They can be either a primary disease or secondary to/triggered by a host of other clinical conditions. We present five interesting cases of paediatric AIHA associated with infections (viral, bacterial and atypical) and autoimmune diseases {Systemic Lupus Erythematosus (SLE) and Autoimmune Hepatitis (AIH)}. The H1N1 influenza associated AIHA responded to oseltamivir and Intravenous Immunoglobulin (IvIg) while the cases secondary to Mycoplasma pneumoniae and pneumococcal bacteraemia required only treatment of the primary infection. AIHA with SLE responded well to corticosteroid therapy but the patient with AIH and AIHA succumbed to severe liver failure. Rest of the four cases with good response to therapy did not have any recurrence/relapse of AIHA during their follow up periods. |
| Databáze: | OpenAIRE |
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