Idiopathic thrombocytopenic purpura in pregnancy: A single institutional experience with maternal and neonatal outcomes
| Autor: | Vildan Ozkocaman, Fahir Özkalemkaş, Ahmet Tunali, Emel Bulbul-Baskan, O. Develioğlu, Yalçın Kimya, Rıdvan Ali, Mehpare Tüfekçi, Tulay Ozcelik, Nilgün Köksal, Ülkü Ozan |
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| Přispěvatelé: | Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Deri ve Zührevi Hastalıklar Anabilim Dalı., Ali, Rıdvan, Özkalemkaş, Fahir, Özçelik, Tülay, Özkocaman, Vildan, Ozan, Ülkü, Kimya, Yalçın, Köksal, Nilgün, Başkan, Emel Bülbül, Develioǧlu, Osman H., Tüfekçi, Mehpare, Tunalı, Ahmet, AAH-1854-2021, AAG-8393-2021, AAG-8595-2021 |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Pediatrics
Platelet count medicine.medical_treatment Patient care team Infant newborn Obstetrics and gynaecology Pregnancy Corticosteroid Purpura thrombocytopenic idiopathic Vaginal delivery Priority journal Fetus death Second trimester pregnancy Pregnancy complications hematologic Idiopathic Thrombocytopenic Purpura Platelet Count Thrombocytopenia General Medicine Hematology Thrombocytopenic purpura Management Fetal death Childbirth Outcomes research Splenectomy Gestation Fetus mortality Delivery obstetric Female Human Adult Drug megadose medicine.medical_specialty Adolescent Twin pregnancy Clinical article Follow-up studies Pathophysiology Pregnancy outcome Article Preeclampsia Fetus Pregnancy complication High risk pregnancy medicine Thrombocyte count Immunoglobulin Humans Neonatology business.industry Adrenal cortex hormones Infant Idiopathic thrombocytopenic purpura (ITP) medicine.disease Prednisone Idiopathic thrombocytopenic purpura business Cesarean section Solutio placentae Controlled study |
| Popis: | We observed 13 pregnant women of 70 females with idiopathic thrombocytopenic purpura (ITP) from January 1992 through September 2002. Thirteen mothers with ITP gave birth to twelve babies and two fetuses died. One of the pregnancies produced twins. Seven of the cases were diagnosed with ITP before pregnancy and six during pregnancy. One of the thirteen pregnancies was complicated by preeclampsia, one by ablatio placentae, and one by intrauterine death. Seven mothers received corticosteroid treatment, four high-dose immunoglobulin therapies, and one underwent splenectomy in the second trimester of gestation. At the time of delivery six mothers had normal platelet counts and seven had low platelet counts. Nine deliveries were by vaginal route and four were by cesarean section. Eleven infants were born with normal platelet counts and one was thrombocytopenic at the time of delivery. No infant showed any clinical signs of hemorrhage and there were no neonatal complications. Two fetuses died; one of them because of ablatio placentae and the other was intrauterine dead. In conclusion, ITP in pregnancy requires the management of two patients, the mother and her baby; hence, the close collaboration of a multidisciplinary group composed of a hematologist, obstetrician, anesthesiologist, and neonatologist is essential. |
| Databáze: | OpenAIRE |
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