Still confused about rose bengal?
Autor: | Monica Berry, Doreen Khan-Lim |
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Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
Diagnosis Differential Cellular and Molecular Neuroscience chemistry.chemical_compound Ophthalmology medicine Rose bengal Humans Fluorescence staining Fluorescent Dyes Rose Bengal Staining and Labeling business.industry Disease progression Dry eyes Impression cytology medicine.disease Dermatology eye diseases Sensory Systems Disease etiology Staining stomatognathic diseases chemistry Disease Progression Dry Eye Syndromes sense organs business Ocular surface Biomarkers |
Zdroj: | Current Eye Research. 29:311-317 |
ISSN: | 1460-2202 0271-3683 |
DOI: | 10.1080/02713680490516864 |
Popis: | We have surveyed the ophthalmic literature of the last five years in an attempt to evaluate the use and usefulness of Rose Bengal staining as an aid to differential diagnosis in dry eyes. Included both as a criterion and as an adjunct measure of disease progression, Rose Bengal scores of patients with different dry eye conditions overlap, sometimes to a considerable extent. A mechanistic link between staining with this dye and disease etiology is unlikely; however, Rose Bengal could be a surrogate marker of changes in ocular surface physiology. The question whether the extent and pattern of staining with Rose Bengal provide the clinician with information not available from other tests, and in particular from fluorescein staining of the ocular surface, has to be answered positively, though the nature of this information is not clearly understood. A more widespread recognition that Rose Bengal is not a vital dye is necessary in order not to bias the interpretation of experimental results. |
Databáze: | OpenAIRE |
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