Iron status at 1 and 6 years versus developmental scores at 6 years in a well-nourished affluent population
| Autor: | Sigurdur J. Gretarsson, B S Gunnarsson, Inga Thorsdottir, Gestur I. Palsson |
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| Rok vydání: | 2007 |
| Předmět: |
Erythrocyte Indices
Male Pediatrics medicine.medical_specialty Longitudinal study Gross motor skill Population Nutritional Status Hemoglobins Child Development Humans Medicine Child education Mean corpuscular volume Motor skill education.field_of_study Anemia Iron-Deficiency medicine.diagnostic_test biology business.industry Infant Iron Deficiencies General Medicine Iron deficiency medicine.disease Ferritin Motor Skills Pediatrics Perinatology and Child Health biology.protein Regression Analysis Female Iron status business |
| Zdroj: | Acta Paediatrica. 96:391-395 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/j.1651-2227.2007.00086.x |
| Popis: | Aim: To examine the association between iron status at 1 and 6 years with development at 6 years. Methods: In a longitudinal study of children (n = 77), iron status was measured at 1 and 6 years and the Icelandic Developmental Inventory, which evaluates children's motor and verbal development, was filled in by mothers near the children's sixth birthday. Results: Children, iron-deficient at 1 year (n = 10), had lower fine motor development scores at 6 years than non–iron-deficient (n = 56) (46.7 ± 4.1 vs. 49.3 ± 2.0; p = 0.011). Fine motor scores were also lower in children with depleted iron stores at 1 year (n = 26) than non–iron-depleted children (n = 40) (48.0 ± 3.3 vs. 49.5 ± 1.8; p = 0.045). Multiple regression analyses, with iron status indices at 6 years, showed that mean corpuscular volume along with male gender predicted significantly positively for expression (adj. R2= 0.15; p = 0.018; n = 73), while regression analyses, including iron status at 1 and 6 years, showed that haemoglobin at 6 years was positively associated with gross motor (adj. R2= 0.05; p = 0.038; n = 63). Conclusions: In an affluent society, iron deficiency and depleted iron stores at 1 year may contribute to worse fine motor developmental scores at 6 years, while low mean corpuscular volume and haemoglobin at 6 years might affect subsequent expression and gross motor scores negatively. Sponsorship: The Icelandic Research Council. |
| Databáze: | OpenAIRE |
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