Novel application of helical tomotherapy in whole skull palliative radiotherapy
| Autor: | T. Coad, Glenn Bauman, George Rodrigues, Slav Yartsev |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_treatment Skull Base Neoplasms Tomotherapy Prostate cancer Radiation Protection Prostate Palliative radiotherapy medicine Humans Radiology Nuclear Medicine and imaging Aged Radiological and Ultrasound Technology business.industry Radiotherapy Planning Computer-Assisted Palliative Care Prostatic Neoplasms Radiotherapy Dosage medicine.disease Spinal cord Radiation therapy Skull medicine.anatomical_structure Oncology Optic nerve business Nuclear medicine Tomography Spiral Computed |
| Zdroj: | Medical dosimetry : official journal of the American Association of Medical Dosimetrists. 33(4) |
| ISSN: | 1873-4022 |
| Popis: | Helical tomotherapy (HT) is a radiation planning/delivery platform that combines inversely planned IMRT with on-board megavoltage imaging. A unique HT radiotherapy whole skull brain sparing technique is described in a patient with metastatic prostate cancer. An inverse HT plan and an accompanying back-up conventional lateral 6-MV parallel opposed pair (POP) plan with corresponding isodose distributions and dose-volume histograms (DVH) were created and assessed prior to initiation of therapy. Plans conforming to the planning treatment volume (PTV) with significant sparing of brain, optic nerve, and eye were created. Dose heterogeneity to the PTV target was slightly higher in the HT plan compared to the back-up POP plan. Conformal sparing of brain, optic nerve, and eye was achieved by the HT plan. Similar lens and brain stem/spinal cord doses were seen with both plans. Prospective clinical evaluation with relevant end points (quality of life, symptom relief) are required to confirm the potential benefits of highly conformal therapies applied to palliative situations such as this case. |
| Databáze: | OpenAIRE |
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