An integral approach to the measurement of glomerular filtration rate
| Autor: | John D. Harries, Keith N. Drummond, A.S. Malowany, Richard R. Mildenberger |
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| Rok vydání: | 1973 |
| Předmět: |
Computers
General Engineering Biomedical Engineering Renal function Human physiology Single injection Urine Integral equation Computer Science Applications law.invention Iodine Radioisotopes Physics::Plasma Physics law Curve fitting Calculus Humans Applied mathematics Blood Chemical Analysis Mathematics Filtration Glomerular Filtration Rate |
| Zdroj: | Medical & Biological Engineering. 11:579-583 |
| ISSN: | 1741-0444 0025-696X |
| DOI: | 10.1007/bf02477402 |
| Popis: | The paper presents a method for the accurate clinical measurement of kidney glomerular filtration rate using a single injection of tracer and the collection of plasma and urine samples. The method is based on an integral-equation approach and is implemented by computerised curve fitting of the plasma-concentration data. The urine-collection procedures are simplified, and errors are reduced. Plasma-only methods are shown to be special cases of the general integral equation, and their limitations are stated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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