Chikungunya Fever Among Patients with Acute Febrile Illness Attending a Tertiary Care Hospital in Mumbai
| Autor: | Lata Baswanna Galate, Vikram A Londhey, Sachee Agrawal, Jayanthi Shastri |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Visual analogue scale 030106 microbiology 030231 tropical medicine lcsh:Medicine medicine.disease_cause Chikungunya fever Dengue fever 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Seroprevalence dual infection Chikungunya seroprevalence business.industry lcsh:R Febrile illness Tertiary care hospital medicine.disease dengue Surgery Joint pain Original Article medicine.symptom business |
| Zdroj: | Journal of Laboratory Physicians Journal of Laboratory Physicians, Vol 8, Iss 02, Pp 085-089 (2016) |
| ISSN: | 0974-2727 |
| Popis: | Background: Chikungunya fever (CHIK) is an arboviral disease. Dengue fever (DENG) and CHIK are indistinguishable clinically and need to be differentiated by laboratory investigations. Purpose: This study aimed at estimating the seroprevalence of CHIK mono-infection and CHIK and DENG dual infection in suspected patients. We also analyzed the age, sex distribution, joint involvement, and relation of joint movement restriction with visual analog scale (VAS). Materials and Methods: Two hundred patients clinically suspected with DENG and CHIK were enrolled from a Tertiary Care Hospital in Mumbai from April 2012 to October 2013. The detailed history and examination findings were recorded. Serum samples were subjected to DENG and CHIK immunoglobulin G (IgM) enzyme-linked immunosorbent assay (ELISA). Results: The seroprevalence of CHIK was 12.5%. Mono-infection of CHIK was 3%, and CHIK and DENG dual infection was 9.5%. Most affected age group in CHIK cases was 46–60 years wherein female preponderance was seen. All 6 patients with CHIK mono-infection had fever and joint involvement; knee and elbow were the most commonly affected joints. All CHIK patients had VAS score of 6–10 with restricted joint movement. Of the patients with dual infection, the majorities were from 31 to 45 years with male preponderance; all had fever and joint pain mainly affecting knee and elbow. Of patients who had VAS score 6–10 in patients with dual infection, only 5.26% had restricted joint movement. Conclusion: IgM ELISA for Chikungunya infection should be included in the routine laboratory tests for acute febrile illness. |
| Databáze: | OpenAIRE |
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