Mechanical hypothesis of sperm penetration
| Autor: | R. D. Purves, D. P. L. Green |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
endocrine system Biophysics Biology Models Biological Sperm penetration Human fertilization medicine Animals Zona pellucida Zona Pellucida reproductive and urinary physiology Sperm-Ovum Interactions Acrosin urogenital system Penetration (firestop) Anatomy Spermatozoa Sperm medicine.anatomical_structure Fertilization embryonic structures Female Mathematics Research Article |
| Zdroj: | Biophysical Journal. 45:659-662 |
| ISSN: | 0006-3495 |
| DOI: | 10.1016/s0006-3495(84)84207-1 |
| Popis: | Sperm have generally been supposed to penetrate the zona pellucida surrounding the mammalian egg with the aid of a protease, acrosin. Difficulties associated with this view are discussed and an alternative, mechanical hypothesis introduced. The calculated force exerted by individual sperm is too small to permit the rupture of any but the weakest of secondary chemical bonds. Mechanical progress through the zona must rely on stress relaxation in a viscoelastic medium. The known properties of the zona appear to be consistent with such a mechanism of penetration. |
| Databáze: | OpenAIRE |
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