Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people
| Autor: | H. Chams, Akiko Miyazaki, Shigeaki Ohno, Daiju Iwata, Miles Stanford, Nobuyoshi Kitaichi |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics genetic structures Epidemiology Eye disease education Ethnic group Prevalence Iris Behcet's disease Disease Middle East Cellular and Molecular Neuroscience medicine Humans Age of Onset Child health care economics and organizations Asia Southeastern Inflammation Public health Choroid Asia Eastern business.industry Behcet Syndrome medicine.disease eye diseases humanities Sensory Systems Surgery Europe Ophthalmology Female Age of onset business Uveitis |
| Zdroj: | British Journal of Ophthalmology. 93:1428-1430 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.2008.154476 |
| Popis: | Asia-Pacific Intraocular Inflammation Study Group (APIISG) Excellent Contribution Young Investigator Award at 3rd Asia-Pacific Intraocular Inflammation (APII) Symposium (5-7 November 2009, Chongqing, China) 第1回アジア太平洋内眼炎症学会最高貢献賞若手研究者賞受賞（国際ぶどう膜炎/アジア太平洋内眼炎合同シンポジウムにて、平成21年11月5日～7日、中国・重慶市） Purpose: There is little information on the demographic and clinical characteristics of Behcet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres. Methods: Descriptive questionnaires were collected from 25 eye centers in 14 countries. The questionnaire surveyed details of juvenile-onset Behcet's disease with uveitis. Ethnic groups, clinical features, treatments, and prognosis of pediatric-age Behcet's disease were examined on a world scale. Results: The clinical data of 135 juvenile-onset and 1,227 adult-onset patients with uveitis were collected. The average age of disease diagnosis in the children was 11.7 years old. Of the ethnic groups identified: 54% were from Middle East, 43% from Europe, but only 2% from East/South Asian countries. By contrast, 19.2% of adult patients were from East or South Asia. The frequency of genital ulcers in juvenile patients was 38.7%, which was significantly lower than in adult cases (53.5%; p < 0.01). Conclusions: Behcet's disease with uveitis was less common in children than in adults in East/South Asia. Although the clinical features of the systemic disease were similar in children and adults, there was a lower frequency of genital ulceration in children. |
| Databáze: | OpenAIRE |
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