Effect of the 'zero' Magnetic Field on Early Embryogenesis in Mice

Autor:	Rita Ya. Gordon, Marina A. Osipenko, Sergei S. Khutzian, L. M. Mezhevikina, Evgenii E. Fesenko
Rok vydání:	2010
Předmět:	Time Factors Offspring Biophysics Uterus Embryonic Development Medicine (miscellaneous) Biology Endometrium Andrology Magnetics Mice Pregnancy medicine Animals Blastocyst reproductive and urinary physiology Zygote urogenital system Trophoblast Embryo General Medicine Embryo Mammalian Embryonic stem cell medicine.anatomical_structure embryonic structures Immunology Female
Zdroj:	Electromagnetic Biology and Medicine. 29:1-8
ISSN:	1536-8386 1536-8378
DOI:	10.3109/15368371003627290
Popis:	It was shown that the 250-fold screening of the geomagnetic field (GMF) ("zero" magnetic field with an induction of 0.2 muT) affects early embryogenesis and the reproduction capacity of mice in vivo. Pregnant NMRI mice at the zygote stage placed in this "zero" magnetic field (MF) lost the ability to bear offspring babies although their embryos developed up to the blastocyst stage without any visible deviations from the norm. The abortion of development in the "zero" MF occurred after the exit of the blastocysts from the zona pellicida and invasion into the uterus during implantation. Histological analysis indicates that possible reasons of the abnormalities of postimplantation development are a decrease in the proliferative activity of embryonic cells and the impairment of the interaction between the trophoblast and endometrium, which finally results in the resorption of embryos in the uterus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38aa1226c561ea8755f3a00b924f0416 https://doi.org/10.3109/15368371003627290 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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