Amorphous carbon nitride microband integrated in a microfluidic device for DNA biosensors applications

Autor: Mathieu Lazerges, Vincent Dupuis, Jean-Michel Siaugue, Alain Pailleret, Marie-Charlotte Horny, Jean Gamby, Claude Deslouis, Florence Billon
Přispěvatelé: Centre de Nanosciences et de Nanotechnologies (C2N), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire Interfaces et Systèmes Electrochimiques (LISE), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS - UM 4 (UMR 8258 / U1022)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), PHysicochimie des Electrolytes et Nanosystèmes InterfaciauX (PHENIX), LabEX MiChem, Gamby, Jean, Institut de Chimie du CNRS (INC)-Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
channel microelectrode
Diamond-like carbon
General Chemical Engineering
[SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics
Microfluidics
microfluidics
chemistry.chemical_element
Nanotechnology
02 engineering and technology
Nitride
[SPI.MAT] Engineering Sciences [physics]/Materials
010402 general chemistry
01 natural sciences
Analytical Chemistry
[SPI.MAT]Engineering Sciences [physics]/Materials
[PHYS] Physics [physics]
Monolayer
Electrochemistry
[PHYS.COND]Physics [physics]/Condensed Matter [cond-mat]
[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics
[PHYS]Physics [physics]
Chemistry
Amorphous Carbon Nitride
021001 nanoscience & nanotechnology
0104 chemical sciences
[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
nucleic acids
[CHIM.THEO] Chemical Sciences/Theoretical and/or physical chemistry
Amorphous carbon
Impedance Spectroscopy
Electrode
0210 nano-technology
Carbon
Biosensor
[PHYS.COND] Physics [physics]/Condensed Matter [cond-mat]
Zdroj: Journal of Electroanalytical Chemistry
Journal of Electroanalytical Chemistry, 2021, 895, pp.115395. ⟨10.1016/j.jelechem.2021.115395⟩
Journal of Electroanalytical Chemistry, Elsevier 2021, pp.115395. ⟨10.1016/j.jelechem.2021.115395⟩
ISSN: 1572-6657
Popis: International audience; This study presents the use of new kind of carbon electrode materials as ultramicroelectrodes (UMEs) in the field of electrochemical DNA biosensors which has already been proven to be effective in protocols to DNA sequences hybridization. In contrast to other carbon materials such as diamond like carbon, that are difficult to integrate in microfluidic devices due to their high temperature deposition, amorphous carbon nitride (a-CNx) is easily synthesized at room temperature on various materials using sputtering techniques. Here, we report a-CNx use as microband electrodes in Glass/PDMS microfluidic devices. a-CNx electrodes were activated and then biofuntionalized by covalent grafting of a DNA probe as self-assembled monolayer (SAM) with a view to future development of a detection platform targeting circulating DNA or RNA sequences in microfluidic channels.
Databáze: OpenAIRE
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