Autologous stem cell transplantation in two children with disabling pansclerotic morphea
Autor: | Nikolaus Rieber, C. Zimmer, Monika Moll, Jasmin B Kuemmerle-Deschner, Ursula Holzer |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Pediatrics
medicine.medical_specialty lcsh:Diseases of the musculoskeletal system Pansclerotic Morphea business.industry lcsh:RJ1-570 lcsh:Pediatrics macromolecular substances medicine.disease Systemic scleroderma Scleroderma Fludarabine Autologous stem-cell transplantation Rheumatology Methylprednisolone Pediatrics Perinatology and Child Health Poster Presentation medicine Immunology and Allergy Methotrexate Pediatrics Perinatology and Child Health Stem cell lcsh:RC925-935 business medicine.drug |
Zdroj: | Pediatric Rheumatology Online Journal Pediatric Rheumatology Online Journal, Vol 9, Iss Suppl 1, p P77 (2011) |
ISSN: | 1546-0096 |
Popis: | Background Disabling pansclerotic morphea is an extremely rare and severe disorder in children, systemic treatment with corticosteroids and methotrexate (MTX) or mycophenolate mofetil (MMF) are the most common therapies. However, patients can develop severe disabilities. Autologous stem cell transplantion (ASCT) is a successful treatment option for systemic scleroderma and might also be beneficial for severe therapy resistant disabling pansclerotic morphea. |
Databáze: | OpenAIRE |
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