Route Learning Performance
| Autor: | Mirna Wetters Portuguez, Arthur A. Pereira-Filho, Luciana Schermann Azambuja, Danielle Irigoyen da Costa, Jaderson Costa da Costa, Adriana Gutterres Pereira, Sabine Possa Marroni |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Cognitive Neuroscience Spatial Behavior Hippocampus Neuropsychological Tests Audiology Hippocampal formation Spatial memory Functional Laterality Temporal lobe Developmental psychology Epilepsy Reference Values Orientation (mental) Orientation medicine Humans Maze Learning Significant difference General Medicine Middle Aged medicine.disease Temporal Lobe Psychiatry and Mental health Neuropsychology and Physiological Psychology Epilepsy Temporal Lobe Case-Control Studies Space Perception Mental Recall Female Analysis of variance Psychology |
| Zdroj: | Cognitive and Behavioral Neurology. 24:4-10 |
| ISSN: | 1543-3633 |
| DOI: | 10.1097/wnn.0b013e318218c3d6 |
| Popis: | Introduction: In temporal lobe epilepsy (TLE), about 30% of the patients do not achieve adequate pharmacologic control of refractory crises, and surgery becomes an alternative. In ablative interventions, neuropsychologic testing of memory is a crucial step. However, evaluations of the right hippocampal functions have not been consistent. Aim: To assess the hippocampal function in remote orientation and visuospatial memory in patients with refractory temporal epilepsy. Methods: A controlled study of patients with left (LTLE) or right (RTLE) TLE. The subjects were submitted to a neuropsychologic evaluation through the Route Learning Test and the Childhood Home Test in the preoperative period. The statistical analysis was performed using the Kruskal-Wallis, analysis of variance, χ 2 , and Mann-Whitney U tests. Results: There was no significant difference in performance in the remote visuospatial memory (as measured by the Childhood Home Test) across the groups (LTLE, RTLE, and control). Concerning the spatial orientation memory, however, there was a significant difference between the LTLE and controls as compared with the RTLE group (P < 0.001), the latter showing a poorer performance. Conclusions: The study suggests that spatial orientation memory relies on the integrity of the right hippocampus. Nevertheless, further studies are necessary to confirm this hypothesis. |
| Databáze: | OpenAIRE |
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