Congenital cataract associated with persistent fetal vasculature: findings from IoLunder2
| Autor: | Ameenat Lola Solebo, Phillippa M. Cumberland, Jugnoo S Rahi, Isabelle Russell-Eggitt |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty genetic structures Population Visual Acuity Glaucoma Aphakia Postcataract Cataract Extraction Persistent Hyperplastic Primary Vitreous Refraction Ocular Aphakia Cataract Cohort Studies Neuro-ophthalmology 03 medical and health sciences 0302 clinical medicine Lens Implantation Intraocular Humans Medicine Prospective Studies Persistent fetal vasculature Prospective cohort study education education.field_of_study business.industry Infant Newborn Infant medicine.disease United Kingdom eye diseases Surgery Ophthalmology 030104 developmental biology Child Preschool Cohort Clinical Study 030221 ophthalmology & optometry business Cohort study |
| Zdroj: | Eye. 30:1204-1209 |
| ISSN: | 1476-5454 0950-222X |
| Popis: | PurposeTo describe the frequency, characteristics, and treatment outcome of persistent fetal vasculature (PFV) in children undergoing surgery for congenital and infantile cataract in the first 2 years of life.Patients and methodsObservational population-based cohort study with case identification through active surveillance and standardised data collection via a national clinical network, the British Isles Congenital Cataract Interest Group (BCCIG).ResultsThe IoLunder2 cohort comprises 246 children undergoing surgery for bilateral and unilateral congenital and infantile cataract in the first 2 years of life. A total of 58/246 (24%) children had PFV (%): overall, 46/95 (46%) with unilateral cataract, and 12/141 (8%) with bilateral disease. Anterior segment vascular remnants were more common in bilateral than unilateral disease (75 vs 11%, P=0.01). At 1 year after surgery, 20% of children with bilateral PFV and 24% with unilateral had achieved normal vision for age within the operated eye. The prevalence of post-operative glaucoma was 9% (of children with bilateral disease) and 4% (unilateral).ConclusionPFV is significantly more common than previously reported, and outcomes are comparable to that for congenital and infantile cataract overall. |
| Databáze: | OpenAIRE |
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