Clinicoepidemiological Features and Mortality Analysis of Deceased Patients with COVID-19 in a Tertiary Care Center
| Autor: | Kapil Dev Soni, Rajesh Malhotra, Venkata Ganesh, Debesh Bhoi, Renjith Viswanath, Nishant Patel, Shailender Kumar, Karthik V Iyer, Manish Soneja, Richa Aggarwal, Purva Mathur, Ridhima Bhatia, Ajisha Aravindan, Yudhyavir Singh, Kshitija Kulshrestha, Naveet Wig, Puneet Khanna, Anjan Trikha, Ashutosh K Singh, Kellika Prakash, Vineeta Venkateswaran, Sulagna Bhattacharjee, Anju Gupta, Rakesh Kumar, Randeep Guleria, Arshed Ayub |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
ARDS
Pediatrics medicine.medical_specialty Clinicoepidemiological features Critical Care and Intensive Care Medicine Comorbidities Sepsis 03 medical and health sciences 0302 clinical medicine Interquartile range Diabetes mellitus Medicine Multi-organ dysfunction syndrome Mortality analysis business.industry 030208 emergency & critical care medicine Retrospective cohort study medicine.disease COVID-19 deceased 030228 respiratory system Cohort ICU Original Article business Multiple organ dysfunction syndrome Kidney disease |
| Zdroj: | Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine |
| ISSN: | 1998-359X 0972-5229 |
| Popis: | Background and objective A large number of studies describing the clinicoepidemiological features of coronavirus disease-2019 (COVID-19) patients are available but very few studies have documented similar features of the deceased. This study was aimed to describe the clinicoepidemiological features and the causes of mortality of COVID-19 deceased patients admitted in a dedicated COVID center in India. Methodology This was a retrospective study done in adult deceased patients admitted in COVID ICU from April 4 to July 24, 2020. The clinical features, comorbidities, complications, and causes of mortality in these patients were analyzed. Pediatric deceased were analyzed separately. Results A total of 654 adult patients were admitted in the ICU during the study period and ICU mortality was 37.7% (247/654). Among the adult deceased, 65.9% were males with a median age of 56 years [interquartile range (IQR), 41.5-65] and 94.74% had one or more comorbidities, most common being hypertension (43.3%), diabetes mellitus (34.8%), and chronic kidney disease (20.6%). The most common presenting features in these deceased were fever (75.7%), cough (68.8%), and shortness of breath (67.6%). The mean initial sequential organ failure assessment score was 9.3 ± 4.7 and 24.2% were already intubated at the time of admission. The median duration of hospital stay was 6 days (IQR, 3-11). The most common cause of death was sepsis with multi-organ failure (55.1%) followed by severe acute respiratory distress syndrome (ARDS) (25.5%). All pediatric deceased had comorbid conditions and the most common cause of death in this group was severe ARDS. Conclusion In this cohort of adult deceased, most were young males with age less than 65 years with one or more comorbidities, hypertension being the most common. Only 5% of the deceased had no comorbidities. Sepsis with multi-organ dysfunction syndrome was the most common cause of death. How to cite this article Aggarwal R, Bhatia R, Kulshrestha K, Soni KD, Viswanath R, Singh AK, et al. Clinicoepidemiological Features and Mortality Analysis of Deceased Patients with COVID-19 in a Tertiary Care Center. Indian J Crit Care Med 2021; 25(6):622-628. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|