Impact of season of diagnosis on mortality among breast cancer survivors
Autor: | Vydmantas Atkočius, Valerijus Ostapenko, Eduardas Aleknavicius, Irena Kuzmickiene |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Prognostic variable medicine.medical_specialty medicine.medical_treatment season of diagnosis Antineoplastic Agents Breast Neoplasms Kaplan-Meier Estimate Models Biological survival lcsh:RC254-282 Cohort Studies 03 medical and health sciences 0302 clinical medicine Breast cancer Cancer Survivors Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Vitamin D Survival rate Proportional Hazards Models Chemotherapy business.industry Proportional hazards model Hazard ratio Age Factors Lithuania General Medicine Middle Aged medicine.disease Prognosis lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Confidence interval Radiation therapy Survival Rate 030104 developmental biology Oncology Chemotherapy Adjuvant 030220 oncology & carcinogenesis Female Seasons business |
Zdroj: | Journal of Cancer Research and Therapeutics, Vol 14, Iss 12, Pp 1091-1097 (2018) |
ISSN: | 1998-4138 0973-1482 |
Popis: | Introduction: There is mounting evidence that the time of breast cancer diagnosis and the start of treatment can improve survival rates. The aim of this study was to test the relationship between the season of breast cancer diagnosis and the survival of women patients receiving standard surgery treatment with radiotherapy. Materials and Methods: The nonmetastatic breast cancer patients (n = 991) were followed from the date of diagnosis until death. Cox proportional hazards models were used to calculate multivariate hazard ratios (HRs) for all-cause mortality. HRs and 95% confidence intervals (CIs) were estimated in models adjusted for clinicopathologic and treatment factors. Results: After adjusting for independent prognostic variables, we found that patients diagnosed in summer and autumn had a 40% reduced risk for 0–3-year mortality when compared to those diagnosed in spring. Among women aged |
Databáze: | OpenAIRE |
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