Truss implant technology™ for interbody fusion in spinal degenerative disorders: profile of advanced structural design, mechanobiologic and performance characteristics
| Autor: | Jon E Block, Matthew R. Begley, Jessee P Hunt |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Technology
Computer science Degenerative Disorder Biophysics Biomedical Engineering Truss 030204 cardiovascular system & hematology Osseointegration Degenerative disc disease 03 medical and health sciences Mechanobiology 0302 clinical medicine medicine Humans Intervertebral Disc Lumbar Vertebrae Intervertebral disc Prostheses and Implants General Medicine medicine.disease Spinal column Spinal Fusion medicine.anatomical_structure Surgery Implant 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | Expert Review of Medical Devices. 18:707-715 |
| ISSN: | 1745-2422 1743-4440 |
| DOI: | 10.1080/17434440.2021.1947244 |
| Popis: | Introduction: Interbody fusion devices are customarily used in fusion of the anterior spinal column for treatment of degenerative disc disease. Their traditional role is to reestablish and maintain intervertebral disc height, contain bone graft and provide mechanical support for the spine while osseointegration takes place. Utilizing the principles of mechanobiology, a unique biokinetic interbody fusion device has been developed that employs an advanced structural design to facilitate and actively participate in the fusion consolidation process.Areas covered: This article profiles and characterizes 4WEB Medical's Truss Implant Technology™ which includes a range of 3D-printed titanium spinal interbody implants and non-spinal implants whose design is based on truss structures enabled by advances in additive manufacturing. Four main areas of the implant design and functionality are detailed: bio-architecture, mechanobiologic underpinnings, bioactive surface features, and subsidence resistance. Pre-clinical and clinical examples are provided to describe and specify the bioactive roles and contributions of each design feature.Expert opinion: The distinct and unique combination of features incorporated within the truss cage design results in a biokinetic implant that actively participates in the bone healing cascade and fusion process. |
| Databáze: | OpenAIRE |
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