Campylobacter‐triggered reactive arthritis: a population‐based study
| Autor: | H. Rautelin, Pirkko Pelkonen, Pekka Lahdenne, Anja Siitonen, L. Mattila, Marjatta Leirisalo-Repo, Timo Hannu |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Bursitis Population Arthritis Physical examination medicine.disease_cause Arthritis Reactive Rheumatology Surveys and Questionnaires Internal medicine Campylobacter Infections Prohibitins medicine Humans Pharmacology (medical) Reactive arthritis Prospective Studies skin and connective tissue diseases education Finland Aged education.field_of_study medicine.diagnostic_test business.industry Enthesopathy Incidence (epidemiology) Campylobacter Middle Aged bacterial infections and mycoses medicine.disease Immunology Female business |
| Zdroj: | Rheumatology. 41:312-318 |
| ISSN: | 1462-0332 1462-0324 |
| DOI: | 10.1093/rheumatology/41.3.312 |
| Popis: | Objective. To study the incidence and clinical picture of Campylobacter-associated reactive arthritis (ReA) and other reactive musculoskeletal symptoms in the population. Methods. A questionnaire on enteric and extraintestinal, including specifically musculoskeletal, symptoms was sent to 870 consecutive patients with Campylobacter-positive stool culture and 1440 matched controls. Analysis of self-reported musculoskeletal symptoms with clinical examination was performed. Results. Forty-five of the patients (7%) had ReA and eight (1%) had reactive tendinitis, enthesopathy or bursitis. No child had ReA. The arthritis was oligo- or polyarticular, and, in most cases, mild. HLA-B27 was positive in 14% of ReA patients. Of the 45 ReA patients, 37 had C. jejuni and 8 had C. coli infection. No controls had ReA. Conclusion. ReA is common following Campylobacter infection, with an annual incidence of 4.3 per 100 000. At the population level, acute ReA is mild, more frequent in adults, and not associated with HLA-B27. Besides C. jejuni, C. coli can trigger ReA. |
| Databáze: | OpenAIRE |
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