No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus
| Autor: | Mona Bungum, Hans Jakob Ingerslev, Jens Fedder, Jens Peter Bonde, Per Höllsberg, Maja Døvling Kaspersen, Peter B. Larsen |
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| Předmět: |
Male
endocrine system viruses Urology Endocrinology Diabetes and Metabolism Semen DNA Fragmentation Biology medicine.disease_cause Polymerase Chain Reaction Herpesviridae law.invention fluids and secretions Endocrinology law medicine Humans Human papillomavirus Papillomaviridae reproductive and urinary physiology Polymerase chain reaction urogenital system biology.organism_classification Sperm Molecular biology Chromatin Reproductive Medicine DNA fragmentation |
| Zdroj: | Scopus-Elsevier Kaspersen, M D, Bungum, M, Fedder, J, Bonde, J, Larsen, P B, Ingerslev, H J & Höllsberg, P 2013, ' No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus ', Andrology, vol. 1, pp. 361-4 . https://doi.org/10.1111/j.2047-2927.2013.00067.x |
| DOI: | 10.1111/j.2047-2927.2013.00067.x |
| Popis: | It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses. |
| Databáze: | OpenAIRE |
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