Origin and outcome of multiple pregnancies in Bern, Switzerland, 1995-2006 and the current proposal of the Swiss parliament to revise the Swiss law of reproductive medicine: Switzerland quo vadis?
Autor: | Martin Birkhäuser, Dorothea Wunder, Mohamed Faouzi, Eva-Maria Neurohr |
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Rok vydání: | 2013 |
Předmět: |
Adult
medicine.medical_specialty Reproductive Techniques Assisted Parliament media_common.quotation_subject Reproductive medicine Maternal morbidity Fertilization in Vitro Multiple Birth Offspring Multinomial logistic regression model Ovulation Induction Pregnancy medicine Single Embryo Transfer Humans media_common Infertility treatments business.industry Pregnancy Outcome General Medicine University hospital Obstetric Labor Complications Pregnancy Complications Logistic Models Reproductive Medicine Neonatal outcomes Law Fertilization Multivariate Analysis Female Pregnancy Multiple business Switzerland Healthcare system |
Zdroj: | Swiss Medical Weekly, vol. 143, pp. w13864 |
ISSN: | 1424-3997 |
Popis: | INTRODUCTION: Infertility treatments are a major source of the increase in multiple pregnancies (MPs). AIMS: The aims of the present study were (1.) to investigate the origin and maternal/neonatal outcomes of MP and (2.) to review the different measures that can be adopted to reduce these serious complications. METHODS: The study included all women with multiple births between 1 January 1995 and 31 December 2006 at the University Hospital of Bern, Switzerland. The outcomes associated with the various origins of MP (natural conception, ovarian stimulation [OS] ‒ in-vitro fertilisation [IVF-ICSI]) were analysed using a multinomial logistic regression model. An analysis of the Swiss law on reproductive medicine and its current proposed revision, as well as a literature review using Pubmed, was carried out. RESULTS: A total of 592 MP were registered, 91% (n = 537) resulted in live births. There was significantly more neonatal/maternal morbidity in MP after OS compared with natural conception and even with the IVF-ICSI group. With a policy of elective single embryo transfer (eSET), twin rates after IVF-ICSI can be reduced to |
Databáze: | OpenAIRE |
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