Hepatoprotective effect of manual acupuncture at acupoint GB34 against CCl4-induced chronic liver damage in rats
| Autor: | Kwoneui Hong, Ji-Young Yi, Byung-Ryul Lee, Yun-Kyoung Yim, Tae-Han Kim, Young-Jin Kim, Hyun Jung Lee |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Acupuncture Therapy CCL4 Pharmacology digestive system Rats sprague dawley Rats Sprague-Dawley chemistry.chemical_compound parasitic diseases Acupuncture Animals Medicine Aspartate Aminotransferases Liver damage Carbon Tetrachloride biology business.industry Gastroenterology Alanine Transaminase General Medicine digestive system diseases Blood Cell Count Rats Sprague dawley Liver chemistry Alanine transaminase Immunology Carbon tetrachloride biology.protein business Acupuncture Points Liver pathology Rapid Communication |
| Zdroj: | World Journal of Gastroenterology. 12:2245 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v12.i14.2245 |
| Popis: | To investigate the hepatoprotective effect of manual acupuncture at Yanglingquan (GB34) on CCl4-induced chronic liver damage in rats.Rats were injected intraperitoneally with CCl4 (1 mL/kg) and treated with manual acupuncture using reinforcing manipulation techniques at left GB34 (Yanglingquan) 3 times a week for 10 wk. A non-acupoint in left gluteal area was selected as a sham point. To estimate the hepatoprotective effect of manual acupuncture at GB34, measurement of liver index, biochemical assays including serum ALT, AST, ALP and total cholesterol, histological analysis and blood cell counts were conducted.Manual acupuncture at GB34 reduced the liver index, serum ALT, AST, ALP and total cholesterol levels as compared with the control group and the sham acupuncture group. It also increased and normalized the populations of WBC and lymphocytes.Manual acupuncture with reinforcing manipulation techniques at left GB34 reduces liver toxicity, protects liver function and liver tissue, and normalizes immune activity in CCl4-intoxicated rats. |
| Databáze: | OpenAIRE |
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