Using a treatment diary to improve the medication adherence in patients with chronic myeloid leukaemia
| Autor: | Fiorenzo Santoleri, Alberto Costantini, Andrea Logreco, Elena Ranucci, Ruggero Lasala |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Pharmacist Dasatinib Medication adherence Antineoplastic Agents Medication Adherence 03 medical and health sciences Young Adult 0302 clinical medicine hemic and lymphatic diseases Internal medicine Leukemia Myelogenous Chronic BCR-ABL Positive Medicine Humans Pharmacology (medical) Prospective Studies Young adult Prospective cohort study Aged business.industry Imatinib Middle Aged Imatinib mesylate Pyrimidines Oncology Nilotinib 030220 oncology & carcinogenesis Imatinib Mesylate Female business 030215 immunology medicine.drug |
| Zdroj: | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 25(5) |
| ISSN: | 1477-092X |
| Popis: | The aim of this study was to verify whether the distribution of a treatment diary by a pharmacist could influence the adherence to oral treatment with imatinib, nilotinib, and dasatinib in patients with chronic myeloid leukaemia.The level of adherence was calculated using the received daily dose/prescribed daily dose ratio and compared between patients who used a diary and those who did not.Forty-four (35.8%) of 123 patients with chronic myeloid leukaemia completed the diary: 20 (45.4%) receiving imatinib, 17 (38.6%) receiving nilotinib, and seven (15.9%) receiving dasatinib. Treatment adherence with the diary calculated using received daily dose/prescribed daily dose method was 93.6% (imatinib 94.9%, nilotinib 91.1%, and dasatinib 95.8%). Adherence during the period without a diary was 86.5% (84.9, 87.4, and 90%). Adherence was significantly greater with than without a diary (p 0.0001).The findings of this study that, in the case of chronic diseases, direct pharmacist-patient contact is important in order to maintain high levels of adherence, and a treatment diary is a valid means of doing this. According to these data, it is necessary to support similar patient-oriented programmes in order to ensure high levels of adherence and optimize drug management. |
| Databáze: | OpenAIRE |
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