Study of Biofilm Growth on Slippery Liquid-Infused Porous Surfaces Made from Fluoropor
| Autor: | Frederik Kotz, Thomas Schwartz, Julia Bruchmann, Dorothea Helmer, Nico Keller, Thomas Sollich, Richard Thelen, Christiane Richter, Bastian E. Rapp |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers Biofilm 02 engineering and technology Surface finish Polymer biochemical phenomena metabolism and nutrition 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Polymerization 0104 chemical sciences Biofouling chemistry Chemical engineering Biofilms Pseudomonas aeruginosa Surface roughness General Materials Science Lubricant 0210 nano-technology Porosity |
| Zdroj: | ACS Applied Materials & Interfaces. 11:4480-4487 |
| ISSN: | 1944-8252 1944-8244 |
| Popis: | Undesired growth of biofilms represents a fundamental problem for all surfaces in long-term contact with aqueous media. Mature biofilms resist most biocide treatments and often are a pathogenic threat. One way to prevent biofilm growth on surfaces is by using slippery liquid-infused porous surfaces (SLIPS). SLIPS consist of a porous substrate which is infused with a lubricant immiscible with the aqueous medium in which the bacteria are suspended. Because of the lubricant, bacteria cannot attach to the substrate surface and thus formation of the biofilm is prevented. For this purpose, we manufactured substrates with different porosity and surface roughness values via UV-initiated free-radical polymerization in Fluoropor. Fluoropor is a class of highly fluorinated bulk-porous polymers with tunable porosity, which we recently introduced. We investigated the growth of the biofilm on the substrates, showing that a reduced surface roughness is beneficial for the reduction of biofilm growth. Samples of low roughness effectively reduced Pseudomonas aeruginosa biofilm growth for 7 days in a flow chamber experiment. The low-roughness samples also become transparent when infused with the lubricant, making such surfaces ideal for real-time observation of biofilm growth by optical examination. |
| Databáze: | OpenAIRE |
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