The Use of Autologous Concentrated Growth Factors to Promote Syndesmosis Fusion in the Agility Total Ankle Replacement. A Preliminary Study
| Autor: | J. David Watts, Craig R. Barrow, Gregory C. Pomeroy, J. Chris Coetzee |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Blood Platelets Male medicine.medical_specialty Syndesmosis Time Factors medicine.medical_treatment 0206 medical engineering Ankle replacement Nonunion MEDLINE 02 engineering and technology 03 medical and health sciences 0302 clinical medicine medicine Humans Orthopedics and Sports Medicine Prospective Studies Arthroplasty Replacement Growth Substances Prospective cohort study Aged Aged 80 and over business.industry 030229 sport sciences Middle Aged medicine.disease 020601 biomedical engineering Arthroplasty Surgery medicine.anatomical_structure Delayed union Physical therapy Female business Ankle Joint |
| Zdroj: | Foot & Ankle International. 26:840-846 |
| ISSN: | 1944-7876 1071-1007 |
| DOI: | 10.1177/107110070502601009 |
| Popis: | Background: The Agility (DePuy, Warsaw, Indiana) total ankle replacement has been in use since 1984. One of the most common complications continues to be delayed union or nonunions of the distal tibiofibular syndesmosis. In the reported studies on the Agility ankle the delayed union and nonunion rate can be as high as 38%. Methods: Since 1999, 114 Agility total ankle replacements were done at two centers in the United States without the use of autologous concentrated growth factors. Since July of 2001, 66 Agility ankles were implanted with Symphony (DePuy, Warsaw, Indiana) augmented bone grafting. The standard operative technique was followed in all the patients. Prospective data was collected on all patients. The standard ankle radiographs were taken preoperatively and postoperative at 8 weeks, 12 weeks, 16 weeks, 6 months, and yearly. CT scans were obtained at 6 months if fusion at the syndesmosis was questionable. The Graphpad Instat software (Graphpad Software Inc., San Diego, CA) was used for statistical analysis. The two-tailed unpaired t-test was used, and the value |
| Databáze: | OpenAIRE |
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