Interactive simulator for pharmacokinetics of repetitive drug dosing
| Autor: | Julius H. Anderson, Glenn A. Iben |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Pharmacology
Dose-Response Relationship Drug Computers Fortran Computer science Variable time Administration Oral Medicine (miscellaneous) Drug administration Injections Intramuscular Models Biological Kinetics Interactive simulation Pharmaceutical Preparations Pharmacokinetics Injections Intravenous Plasma concentration Data file Drug dosing Humans Infusions Parenteral computer Simulation computer.programming_language |
| Zdroj: | Computer Programs in Biomedicine. 4:113-120 |
| ISSN: | 0010-468X |
| DOI: | 10.1016/0010-468x(75)90013-6 |
| Popis: | DRUGSIM is a highly interactive program allowing simulation of the effects of repeated drug administration by a variety of routes on plasma concentrations of drugs over a period of time. Drug parameters are read from a data file; prescriptions are obtained from the user at various points during run time. The results for one or two compartment pharmacokinetics are plotted on a storage display tube, and the user is queried for further prescriptions. Simulation involves a point-slope method with a variable time step. The program is written in Fortran IV and run on a DEC PDP-10 computer using a Computek 611 display terminal. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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