Measurement of intact parathormone during operation for primary hyperparathyroidism
| Autor: | Fialová M, J Sedy, Pavel Pafko, Svatopluk Adámek, Broulík P, Robert Lischke, D Yershov, P Libansky, Jozef Kubinyi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Parathyroidectomy Economics and Econometrics medicine.medical_specialty medicine.medical_treatment Urology Parathyroid Hyperplasia Baseline level Preoperative examination Monitoring Intraoperative Materials Chemistry Media Technology medicine Humans Postoperative Period Prospective Studies Prospective cohort study Aged business.industry Forestry Middle Aged Hyperparathyroidism Primary medicine.disease Thyroid Diseases Treatment Outcome medicine.anatomical_structure Parathyroid Hormone Thyroidectomy Female Parathyroid gland business Primary hyperparathyroidism Persistent hyperparathyroidism |
| Zdroj: | Bratislava Medical Journal. 118:255-257 |
| ISSN: | 1336-0345 |
| DOI: | 10.4149/bll_2017_050 |
| Popis: | In this prospective study, the role of the intact parathormone (iPHT) levels for the verification of pathologic parathyroid tissue removal during parathyroidectomy, was analyzed in 441 patients diagnosed with primary hyperparathyroidism. The level of intact parathormone was obtained before the initial incision (baseline level) and 10 minutes after the pathologic parathyroid gland removal (control value). In 80 % of cases, the decrease of intact parathormone was more than 50 % of the baseline level. The comparison of preoperative and postoperative intact parathormone levels can also be used as marker of parathyroid hyperplasia or persistent hyperparathyroidism. This method is necessary mainly for performance of focused, miniinvasive approaches as well as in reoperations. This method is of significant benefit in cases of negative preoperative examination methods. The determination of intact parathormone level increases the success of parathyroidectomy (Ref. 26). |
| Databáze: | OpenAIRE |
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