Bispectral analysis of the electroencephalogram during induction of anesthesia may predict hemodynamic responses to laryngoscopy and intubation
| Autor: | V. Sinai, Lee A. Kearse, P. Manberg, N. Chamoun, F. deBros |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_treatment Laryngoscopy Hemodynamics Blood Pressure Anesthesia General Electroencephalography Heart Rate Heart rate Intubation Intratracheal Humans Medicine Intubation medicine.diagnostic_test business.industry General Neuroscience Brain Signal Processing Computer-Assisted Middle Aged Blood pressure Bispectral index Anesthesia Bispectral analysis Female Neurology (clinical) business |
| Zdroj: | Electroencephalography and Clinical Neurophysiology. 90:194-200 |
| ISSN: | 0013-4694 |
| Popis: | The use of electroencephalography as a measure of adequacy of anesthesia has achieved limited success. Our purpose was to determine whether the non-linear properties of the electroencephalogram (EEG) as defined by the bispectral index was a better predictor of autonomic responses to endotracheal intubation during opioid-based anesthesia than the linear statistical properties of the EEG formulated by power spectral analysis. Thirty-nine adults scheduled for elective non-cranial surgery had a continuous EEG recorded during induction of anesthesia and endotracheal intubation. Anesthesia consisted of thiopental and nitrous oxide in oxygen, followed by 1 of 5 randomized opioid dose regimens. The EEG was continuously recorded and blood pressure was measured every minute. All electroencephalographic parameters were derived for the 3 min before and after intubation and were compared to the blood pressure and heart rate responses. Responders were defined by 2 analyses: patients who had a 20% or greater increase (1) in blood pressure or (2) in heart rate to laryngoscopy. Responders and non-responders were compared using Student's unpaired t test, and differences due to dose regimens were examined with logistic regression. Based on the criterion for blood pressure change, there were 27 responders and 12 non-responders. Heart rate changes did not differentiate between the two groups. There was a significant difference between response groups as measured by the bispectral index which distinguished responders from non-responders independently of the amount of drug given. None of the variables of power spectral analysis accurately distinguished responder from non-responder. We conclude that the bispectral index of the EEG may accurately predict blood pressure responses in patients undergoing endotracheal intubation after induction of general anesthesia. |
| Databáze: | OpenAIRE |
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