Validasi Metode Bioanalisis Vankomisin HCl dalam Spiked-plasma Manusia Menggunakan KCKT-UV untuk Aplikasi PKOD
| Autor: | Damas Inggil Maulidina, Wahyuni Shalatan Fitri, Ari Wibowo, Vitarani Dwi Ananda Ningrum |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Bioanalysis
medicine.drug_class business.industry Antibiotics Aplikasi PKOD Pharmacology biochemical phenomena metabolism and nutrition medicine.disease_cause Plasma Therapeutic index Vankomisin Validasi Metode KCKT detektor UV medicine Vancomycin lcsh:Q lcsh:Science lcsh:Science (General) business Staphylococcus lcsh:Q1-390 medicine.drug |
| Zdroj: | EKSAKTA: Jurnal Ilmu-ilmu MIPA; VOLUME 19, ISSUE 1, February 2019; 57-70 Eksakta: Jurnal Ilmu-Ilmu MIPA, Vol 19, Iss 1, Pp 57-70 (2019) |
| ISSN: | 1411-1047 2503-2364 |
| Popis: | As the first-line antibiotic for the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA), vancomycin has a narrow therapeutic index with high pharmacokinetic variability. Therefore, it is deemed necessary to examine its concentration in the blood as a strategy to monitor the fulfillment of therapeutic levels in patients receiving vancomycin. This study aimed to validate vancomycin bioanalysis in spiked-human plasma for the applications of therapeutic drug monitoring (TDM). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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