Symptomatic hemiparkinsonism due to extensive middle and posterior fossa arachnoid cyst: case report
Autor: | Gregor K. Wenning, Klaus Seppi, Stephanie Mangesius, Sarah Iglseder, Elke R. Gizewski, Werner Poewe, Bernadette Wimmer, Martin Ortler, Franziska Di Pauli |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty Neurology Decompression Case Report Physical examination Neurosurgical Procedures lcsh:RC346-429 03 medical and health sciences 0302 clinical medicine medicine Humans lcsh:Neurology. Diseases of the nervous system Retrospective Studies 030304 developmental biology 0303 health sciences Pramipexole medicine.diagnostic_test business.industry Parkinsonism Parkinson Disease General Medicine Middle Aged Decompression Surgical medicine.disease 3. Good health Hydrocephalus nervous system diseases Arachnoid Cysts Basal ganglia Neurology (clinical) Radiology Neurosurgery Headaches medicine.symptom Tomography X-Ray Computed business Fenestration Brainstem 030217 neurology & neurosurgery medicine.drug |
Zdroj: | BMC Neurology, Vol 20, Iss 1, Pp 1-4 (2020) BMC Neurology |
ISSN: | 1471-2377 |
DOI: | 10.1186/s12883-020-01670-y |
Popis: | Introduction Intracranial neoplasms are an uncommon cause of symptomatic parkinsonism. We here report a patient with an extensive middle and posterior fossa arachnoid cyst presenting with parkinsonism that was treated by neurosurgical intervention. Methods Retrospective chart review and clinical examination of the patient. Case report This 55-year-old male patient with hemiparkinsonism and recurrent bouts of headaches was first diagnosed in 1988. CT scans revealed multiple cystic lesions compressing brainstem and basal ganglia, which were partially resected. Subsequently, the patient was free of complaints for 20 years. In 2009 the patient presented once more with severe unilateral tremor and thalamic pain affecting the right arm. Despite symptomatic treatment with L-Dopa and pramipexole symptoms worsened over time. In 2014 there was further progression with increasing hemiparkinsonism, hemidystonia, unilateral thalamic pain and pyramidal signs. Repeat CT scanning revealed a progression of the cysts as well as secondary hydrocephalus. Following repeat decompression of the brainstem and fenestration of all cystic membranes parkinsonism improved with a MDS- UPDRS III score reduction from 39 to 21. Histology revealed arachnoid cystic material. Conclusion We report on a rare case of recurrent symptomatic hemiparkinsonism resulting from arachnoid cysts. |
Databáze: | OpenAIRE |
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