Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease
| Autor: | William D. O'Brien, Michael P. Andre, Aiguo Han, Ethan Z. Sy, Claude B. Sirlin, Rohit Loomba, Yassin Labyed, John W. Erdman, Andrew S. Boehringer |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Reproducibility of results Intraclass correlation Image Processing Phantoms 030218 nuclear medicine & medical imaging Imaging 0302 clinical medicine Computer-Assisted Non-alcoholic Fatty Liver Disease Image Processing Computer-Assisted Medicine Prospective Studies Ultrasonography Observer Variation medicine.diagnostic_test Phantoms Imaging Liver Disease Ultrasound General Medicine Middle Aged Nuclear Medicine & Medical Imaging Liver Elasticity Imaging Techniques 030211 gastroenterology & hepatology Female Radiology Elastography Adult medicine.medical_specialty Coefficient of variation Chronic Liver Disease and Cirrhosis Liver fibrosis Clinical Sciences Article Imaging phantom 03 medical and health sciences Clinical Research Humans Radiology Nuclear Medicine and imaging Reproducibility Analysis of Variance business.industry Reproducibility of Results Confidence interval Sonographer Digestive Diseases business Software |
| Zdroj: | European radiology, vol 28, iss 12 Eur Radiol Han, A; Labyed, Y; Sy, EZ; Boehringer, AS; Andre, MP; Erdman, JW; et al.(2018). Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease.. European radiology, 28(12), 4992-5000. doi: 10.1007/s00330-018-5541-9. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/53n7r9n3 |
| Popis: | To assess inter-sonographer reproducibility of ultrasound attenuation coefficient (AC), backscatter coefficient (BSC) and shear wave speed (SWS) in adults with known/suspected non-alcoholic fatty liver disease (NAFLD). The institutional review board approved this HIPAA-compliant prospective study; informed consent was obtained. Participants with known/suspected NAFLD were recruited and underwent same-day liver examinations with a clinical scanner. Each participant was scanned by two of the six trained sonographers. Each sonographer performed multiple data acquisitions in the right liver lobe using a lateral intercostal approach. A data acquisition was a single operator button press that recorded a B-mode image, radio-frequency data, and the SWS value. AC and BSC were calculated from the radio-frequency data using the reference phantom method. SWS was calculated automatically using product software. Intraclass correlation coefficient (ICC) and within-subject coefficient of variation (wCV) were calculated for applicable metrics. Sixty-one participants were recruited. Inter-sonographer ICC was 0.86 (95% confidence interval: 0.77–0.92) for AC and 0.87 (0.78–0.92) for log-transformed BSC (logBSC = 10log10BSC) using one acquisition per sonographer. ICC was 0.88 (0.80–0.93) for both AC and logBSC averaging 5 acquisitions. ICC for SWS was 0.57 (0.29–0.74) using one acquisition per sonographer, and 0.84 (0.66–0.93) using 10 acquisitions. The wCV was ~7% for AC, and 19–43% for SWS, depending on number of acquisitions. Hepatic AC, BSC and SWS measures on a clinical scanner have good inter-sonographer reproducibility in adults with known or suspected NAFLD. Multiple acquisitions are required for SWS but not AC or BSC to achieve good inter-sonographer reproducibility. • AC, BSC and SWS measurements are reproducible in adults with NAFLD. • Inter-sonographer reproducibility of SWS measurement improves with more acquisitions being averaged. • Multiple acquisitions are required for SWS but not AC or BSC. |
| Databáze: | OpenAIRE |
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