Impact of COVID-19 pandemic on the management of paediatric inflammatory bowel disease: An Italian multicentre study on behalf of the SIGENP IBD Group

Autor: Fortunata Civitelli, Matteo Bramuzzo, Claudia Banzato, Stefano Martelossi, Anna Dilillo, Maurizio Fuoti, Rosaria Celano, Caterina Strisciuglio, Claudio Romano, A. Marseglia, Sara Renzo, Massimo Martinelli, Simona Gatti, Lorenzo Norsa, Paolo Lionetti, Serena Arrigo, Erminia Romeo, P. Alvisi, Federica Mario, Enrico Felici, Daniela Knafelz, Roberto Panceri, Giulia D'Arcangelo, Valeria Dipasquale, Chiara Moretti
Přispěvatelé: Arrigo, S., Alvisi, P., Banzato, C., Bramuzzo, M., Celano, R., Civitelli, F., D'Arcangelo, G., Dilillo, A., Dipasquale, V., Felici, E., Fuoti, M., Gatti, S., Knafelz, D., Lionetti, P., Mario, F., Marseglia, A., Martelossi, S., Moretti, C., Norsa, L., Panceri, R., Renzo, S., Romano, C., Romeo, E., Strisciuglio, C., Martinelli, M.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Inflammatory bowel disease
Endoscopy
Gastrointestinal
lockdown
Immunosuppressive Agent
0302 clinical medicine
Crohn Disease
Recurrence
Pandemic
Gastrointestinal Agent
Disease management (health)
Child
immunosuppression
Alimentary Tract
Gastroenterology
Disease Management
Telemedicine
Hospitalization
Italy
Paediatric
030220 oncology & carcinogenesis
Cohort
Biological Product
030211 gastroenterology & hepatology
Electronic data
Female
Immunosuppressive Agents
Human
medicine.medical_specialty
Referral
Coronavirus disease 2019 (COVID-19)
Adolescent
03 medical and health sciences
Gastrointestinal Agents
medicine
Humans
Biological Products
Hepatology
business.industry
SARS-CoV-2
Inflammatory Bowel Disease
COVID-19
Paediatrics
medicine.disease
Inflammatory Bowel Diseases
digestive system diseases
Emergency medicine
Colitis
Ulcerative
business
Zdroj: Digestive and Liver Disease
ISSN: 1590-8658
DOI: 10.1016/j.dld.2020.12.011
Popis: Background: IBD management has been significantly affected during the COVID-19 lockdown with potential clinical issues. Aims: The aim of this study was to analyse the impact of COVID-19 pandemic on the Italian paediatric IBD cohort. Methods: This was a multicentre, retrospective, cohort investigation including 21 different Italian IBD referral centres. An electronic data collection was performed among the participating centres including: clinical characteristics of IBD patients, number of COVID-19 cases and clinical outcomes, disease management during the lockdown and the previous 9 weeks. Results: 2291 children affected by IBD were enrolled. We experienced a significant reduction of the hospital admissions [604/2291 (26.3%) vs 1281/2291 (55.9%); p < 0.001]. More specifically, we observed a reduction of hospitalizations for new diagnosis (from n = 44 to n = 27) and endoscopic re-evaluations (from n = 46 to n = 8). Hospitalization for relapses and surgical procedures remained substantially unchanged. Biologic infusions did not significantly vary [393/2291 (17.1%) vs 368/2291 (16%); p = 0.3]. Telemedicine services for children with IBD were activated in 52.3% of the centres. In 42/2291(1.8%) children immunosuppressive therapies were adapted due to the concurrent COVID-19 pandemic. Conclusion: Due to the several limitations of the lockdown, cares for children with IBD have been kept to minimal standards, giving priorities to the urgencies and to biologics’ infusions and implementing telemedicine services.
Databáze: OpenAIRE
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