Predictors of Remission in Acute and Continuation Treatment of Depressive Disorders
| Autor: | Sung-Wan Kim, Il-Seon Shin, Hee-Ju Kang, Min Jhon, Ha-Yeon Kim, Ju-Wan Kim, Jae-Min Kim, Hee-Joon Lee, Ju-Yeon Lee |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis business.industry Depression Remission University hospital Pharmacotherapy Behavioral Neuroscience Psychiatry and Mental health Social support Rating scale Internal medicine medicine Pharmacology (medical) CONTINUATION TREATMENT Original Article Prospective cohort study business Depression (differential diagnoses) Prediction |
| Zdroj: | Clinical Psychopharmacology and Neuroscience |
| ISSN: | 2093-4327 1738-1088 |
| Popis: | Objective To identify factors predicting remission of depression during acute (12 weeks) and continuation treatment (12 months) using a 1-year, naturalistic prospective study design. Methods Patients with depressive disorders were recruited from Chonnam National University Hospital in South Korea from March 2012 to April 2017. At baseline, 1,262 patients received outpatient therapy, and sociodemographic and clinical data were obtained. Clinical visits took place every 3 weeks during the acute treatment phase (at 3, 6, 9, and 12 weeks; n = 1,246), and every 3 months during the continuation treatment phase (at 6, 9, and 12 months; n = 1,015). Remission was defined as a Hamilton Depression Rating Scale score ≤ 7. Results The remission rate was 43.3% at 12 weeks and 70.4% at 12 months. In multivariate analyses, remission during the acute treatment phase was more likely in patients with a shorter-duration present episode, higher functioning, and good social support. Remission during the continuation treatment phase was more likely in patients with fewer previous depressive episodes and/or a lower baseline stress score. Conclusion Factors predicting depressive disorder remission may differ between the acute and continuation treatment phases. |
| Databáze: | OpenAIRE |
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